Piperidine, 3-phenyl-
3-Phenylpiperidine
CAS: 3973-62-4
Molecular Formula: C11H15N
Piperidine, 3-phenyl- - Names and Identifiers
| Name | 3-Phenylpiperidine |
| Synonyms | ChemDiv2_003191 EINECS 223-602-7 3-PHENYLPIPERIDINE 3-Phenylpiperidine CHEMBRDG-BB 4003675 TIMTEC-BB SBB010187 Piperidine, 3-phenyl- (Piperidin-3-yl)benzene (3R)-3-phenylpiperidinium (3S)-3-cyclohexylpiperidinium |
| CAS | 3973-62-4 |
| EINECS | 223-602-7 |
| InChI | InChI=1/C11H21N/c1-2-5-10(6-3-1)11-7-4-8-12-9-11/h10-12H,1-9H2/p+1/t11-/m1/s1 |
Piperidine, 3-phenyl- - Physico-chemical Properties
| Molecular Formula | C11H15N |
| Molar Mass | 161.24 |
| Density | 0.967 |
| Melting Point | 142-143℃ |
| Boling Point | 121°C/9mm |
| Flash Point | 116℃ |
| Vapor Presure | 0.0237mmHg at 25°C |
| Appearance | clear liquid |
| Color | Colorless to Almost colorless |
| pKa | 10.01±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.5256 |
| MDL | MFCD00804860 |
Piperidine, 3-phenyl- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Class | IRRITANT |
Piperidine, 3-phenyl- - Introduction
3-Phenylpiperidine(3-phenylpiperidine) is an organic compound with the formula C12H15N. The following is a description of its nature, use, preparation and safety information:
1. nature:
-Appearance: 3-Phenylpiperidine is a colorless to light yellow liquid.
-Solubility: It is soluble in most organic solvents, such as ethanol, chloroform and carbon disulfide.
-Melting point and boiling point: Its melting point is -35°C, and its boiling point is 187-189°C.
-Density: Its density is 0.979g/cm³.
2. use:
-Drug synthesis: 3-Phenylpiperidine is an important intermediate compound, which is used as raw material in drug synthesis, especially in the synthesis of some antihistamines such as diphenhydramine and isopropyphenamine.
-Chemical research: It can also be used as a reagent for some organic synthesis reactions, such as reduction reactions and addition reactions of carbonyl compounds.
3. Preparation method:
-Reduction method: 3-Phenylpiperidine can be obtained by the reduction reaction of benzaldehyde. One common method is to carry out the reaction using an excess of hydrogen and sodium or potassium hydride as the reducing agent, at a suitable temperature and pressure.
4. Safety Information:
-Risk warning: 3-Phenylpiperidine may be irritating to the eyes and skin, and may cause damage to the body.
-Precautions for use: Avoid direct contact with skin, eyes and respiratory tract during use. Operate in a well-ventilated area and wear appropriate personal protective equipment.
-Storage precautions: 3-Phenylpiperidine should be stored in a sealed container, away from fire and oxidizing agents, and stored in a dry, cool place.
-Waste disposal: waste should be disposed of in accordance with the prescribed method and should not be dumped at will.
Please note that chemical experiments and the use of chemical substances need to strictly follow the experimental procedures and safe operation guidelines to ensure their own safety and environmental protection.
1. nature:
-Appearance: 3-Phenylpiperidine is a colorless to light yellow liquid.
-Solubility: It is soluble in most organic solvents, such as ethanol, chloroform and carbon disulfide.
-Melting point and boiling point: Its melting point is -35°C, and its boiling point is 187-189°C.
-Density: Its density is 0.979g/cm³.
2. use:
-Drug synthesis: 3-Phenylpiperidine is an important intermediate compound, which is used as raw material in drug synthesis, especially in the synthesis of some antihistamines such as diphenhydramine and isopropyphenamine.
-Chemical research: It can also be used as a reagent for some organic synthesis reactions, such as reduction reactions and addition reactions of carbonyl compounds.
3. Preparation method:
-Reduction method: 3-Phenylpiperidine can be obtained by the reduction reaction of benzaldehyde. One common method is to carry out the reaction using an excess of hydrogen and sodium or potassium hydride as the reducing agent, at a suitable temperature and pressure.
4. Safety Information:
-Risk warning: 3-Phenylpiperidine may be irritating to the eyes and skin, and may cause damage to the body.
-Precautions for use: Avoid direct contact with skin, eyes and respiratory tract during use. Operate in a well-ventilated area and wear appropriate personal protective equipment.
-Storage precautions: 3-Phenylpiperidine should be stored in a sealed container, away from fire and oxidizing agents, and stored in a dry, cool place.
-Waste disposal: waste should be disposed of in accordance with the prescribed method and should not be dumped at will.
Please note that chemical experiments and the use of chemical substances need to strictly follow the experimental procedures and safe operation guidelines to ensure their own safety and environmental protection.
Last Update：2024-04-09 15:17:57
Supplier List
Product Name: 3-Phenylpiperidine Visit Supplier Webpage Request for quotation
CAS: 3973-62-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 3973-62-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 3-Phenylpiperidine Visit Supplier Webpage Request for quotation
CAS: 3973-62-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 3973-62-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History